엑소좀은 노화 또는 질병에 의한 심장 세포의 변성을 방지하고 재생을 촉진하는 회복기능을 가집니다.
| 근거 논문: | |
|---|---|
| 2011 | Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease |
| 2017 | Circulating exosome microRNA associated with heart failure secondary to myxomatous mitral valve disease in a naturally occurring canine model |
| 2019 | The clinical impact of exosomes in cardiovascular disorders: from basic science to clinical application |
| The therapeutic and diagnostic role of exosomes in cardiovascular diseases | |
| 2020 | Circulating exosomal microRNAs as emerging non‐invasive clinical biomarkers in heart failure: mega bio‐roles of a nano bio‐particle |
| 2022 | Exosomes in Dogs and Cats: An innovative approach to neoplastic and non-neoplastic diseases |
| MicroRNAs and exosomes: Cardiac stem cells in heart diseases | |
신기능을 증진시키고, 산화적 손상 및 염증을 줄여주며 신장 조직의 재생과 복구를 도와줍니다.
| 근거 논문: | |
|---|---|
| 2015 | Exosomes as renal inductive signals in health and disease, and their application as diagnostic markers and therapeutic agents |
| 2017 | Urinary exosome-derived microRNAs reflecting the changes of renal function and histopathology in dogs |
| 2018 | Mesenchymal stem cell-derived exosomes ameliorated diabetic nephropathy by autophagy induction through the mTOR signaling pathway |
| 2019 | Potential and therapeutic efficacy of cell-based therapy using mesenchymal stem cells for acute/chronic kidney disease, |
| 2020 | Variability in the cleavage of exosome-associated transferrin receptor questions the utility of clinically useful soluble transferrin receptor assays for dogs, cats, and horses, |
| 2021 | Exosomes in Dogs and Cats: An innovative approach to neoplastic and non-neoplastic diseases |
| The multi-therapeutic role of MSCs in diabetic nephropathy | |
| 근거 논문: | |
|---|---|
| 2020 | Comparative analysis and characterization of soluble factors and exosomes from cultured adipose tissue and bone marrow mesenchymal stem cells in canine species |
| 2021 | Stem cells and exosomes: new therapies for intervertebral disc degeneration |
| 2022 | Evaluation of cutaneous and circulating (serum and exosomes) levels of chemokines (CCL17, CCL22, CCL27 and CCL28) in atopic dogs and their correlation with severity of the disease |
| Mesenchymal stromal/stem cells and their exosomes application in the treatment of intervertebral disc disease: A promising frontier | |
| New strategies for the treatment of intervertebral disc degeneration: cell, exosome, gene, and tissue engineering | |
| 2023 | Recent advance in mesenchymal stem cells therapy for atopic dermatitis |
